From Pathways to Practice: Pharmacists Bridging Pathophysiology, Treatment, and Therapy Escalation in Pulmonary Arterial Hypertension Management
Although recent treatment advances in pulmonary arterial hypertension (PAH) have improved patient quality of life and extended survival, prognoses remain poor. Pharmacists play a key role in facilitating access to clinically appropriate PAH medications and supporting patients to maximize their benefits and safety. Advancing patient-centered education and interprofessional coordination to support safe and effective medication use continues to present challenges in pharmacist management of patients with PAH. As crucial educators on disease management, pharmacists require up-to-date knowledge on PAH pathophysiology, therapy optimization, and guideline recommendations so they can support patients in understanding their medications, monitor their effects, and adhere to treatment regimens. This educational activity will provide in-depth knowledge of the pathophysiological pathways involved in the development of PAH along with distinct mechanisms targeted by PAH therapies and their role in different clinical scenarios. This activity will demonstrate practical strategies for implementing current recommendations for risk stratification and therapy selection, including when and how to escalate therapy including combination therapy to reach patient-centered treatment goals.
Monday, Dec. 7
11:30 a.m. - 1 p.m. ET
Symposium Location: Level 1, Orange County Convention Center, West Building
Come early! Seating is limited and provided on a first-come, first-served basis.
Can't make it to Orlando? Tune into the Free Live Webinar Broadcast.
Registration is required for the webinar.
Speakers
Jared Frost, PharmD, BCCP, Activity Chair
Clinical Pharmacy Specialist– Cardiology
Cardiology Pharmacy Residency Director
Advocate Health – Aurora St. Luke's Medical Center
Milwaukee, Wisconsin
Jared Frost is a Clinical Pharmacy Specialist in cardiology and the PGY2 Cardiology Residency Program Director at Aurora St. Luke's Medical Center in Milwaukee, WI. Dr. Frost earned his Doctor of Pharmacy degree from Drake University and completed both PGY1 and PGY2 Cardiology Pharmacy Residencies at Aurora St. Luke's. In his current role, he oversees medication practices across the cardiac catheterization and electrophysiology labs, cardiovascular surgery, and pulmonary hypertension services. Dr. Frost is an active member of the American College of Cardiology, the National Lipid Association, and the Pharmacy Society of Wisconsin.
Zachary Klick, PharmD, BCCP, BCPS, BCACP, CPP
Cardiology Pharmacist
Cardiology Pharmacy Residency Program Director
Atrium Health Wake Forest Baptist
Winston Salem, North Carolina
Zachary Klick is a board-certified clinical pharmacist specializing in cardiology in Winston-Salem, North Carolina. He earned his PharmD from Duquesne University Mylan School of Pharmacy and completed his PGY1 residency at Carilion Clinic Roanoke Memorial Hospital, followed by a PGY2 cardiology residency at HCA/UTHSC. Dr. Klick has experience in both inpatient and outpatient cardiology, managing patients with advanced heart failure, pulmonary hypertension, and coronary artery disease.
Target Audience
This activity was planned to meet the educational needs of pharmacists who practice in hospitals, health systems, ambulatory clinics, and community settings who care for or are interested in the care of patients with pulmonary arterial hypertension.
Learning Objectives
- Differentiate pathophysiological pathways involved in the development of PAH and medications used for treatment.
- Assess guideline recommendations and emerging clinical evidence to inform medication selection and treatment escalation based on individualized risk assessment.
- Recommend implementation strategies for patient education and monitoring to optimize safety, effectiveness, and adherence with PAH medications.
Agenda
- 11:30 a.m. – Welcome and Introductions
Jared Frost - 11:35 a.m. – Examining the Options: How Mechanisms of Action Shape PAH Treatment Regimens
Jared Frost - 11:50 a.m. – All About Risk: PAH Guideline Recommendations and Evidence in Practice
Zachary Klick - 12:20 p.m. – Collaborate and Listen: Conversations to Improve Safety for Patients with PAH
All Faculty - 12:50 p.m. – Faculty Discussion, Questions and Answers
All Faculty
Accredited for CPE
ACPE #: 0204-0000-26-417-L01-P
CE Credit: 1.5 contact hours (0.15 CEUs)
Activity Type: Application-based
Activity Fee: No charge
To Claim CE for the webinar, enter the CE code announced during the activity and complete the evaluation.
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The American Society of Health-System Pharmacists is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education with Commendation. |
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Provided by ASHP.
Supported by an educational grant from Merck. For questions and assistance to participate, contact us. |

